factor xii

Thân thiện

Factor XII is a protein in the blood that helps initiate the formation of a clot when a vessel is damaged.

Definition

1. Noun:
   • A coagulation factor: Factor XII is a specific protein present in blood plasma that plays a role in the coagulation cascade, which is the process by which blood clots.
   • A substance whose deficiency causes a specific condition: A deficiency or lack of Factor XII in the blood results in a prolonged clotting time for venous blood, meaning it takes longer than normal for a clot to form.

Usage Examples

• Noun:
  • The doctor ordered a test to check the patient's Factor XII levels.
  • Hereditary deficiency of Factor XII is a rare condition.
  • Factor XII is also known as Hageman factor.

Advanced Usage

• In medical diagnostics: The term is used to describe a specific lab finding or a component of a coagulation panel.
  • The prolonged activated partial thromboplastin time (aPTT) was investigated and found to be due to Factor XII deficiency.
• In research contexts: Often discussed in studies of blood coagulation pathways and disorders.
  • The study examined the role of Factor XII in thrombosis.

Variants and Related Words

• Hageman factor: Another name for Factor XII.
• Coagulation factor: The general category to which Factor XII belongs. Other examples include Factor VIII and Factor IX.
• Factor XII deficiency: The medical condition resulting from insufficient levels of this protein.

Synonyms

• Hageman factor: This is a direct synonym, named after the first patient diagnosed with its deficiency.
• Plasma thromboplastin antecedent (PTA): An older, less common synonym.

Related Phrases

• Contact activation pathway: The intrinsic pathway of coagulation, which Factor XII helps initiate.
• Prolonged clotting time: A key clinical effect of Factor XII deficiency.

Học thuật

Noun

1. coagulation factor whose deficiency results in prolongation of clotting time of venous blood

Từ đồng nghĩa

• Hageman factor
• factor XII